This is an update of the mock posted on Saturday because of various moves made. Changes at #3, #4, #19, #27 and #28.
| # | Team | Pick | |
| 1 | Detroit Lions (0-16) | Matt Stafford, QB, Georgia | |
| 2 | St. Louis Rams (2-14) | Jason Smith, OT, Baylor | |
| 3 | Kansas City Chiefs (2-14) | Michael Crabtree, WR, Texas Tech | |
| 4 | Seattle Seahawks (4-12) | Aaron Curry, LB, Wake Forest | |
| 5 | Cleveland Browns (4-12) | Brian Orakpo, DE/OLB, Texas | |
| 6 | Cincinnati Bengals (4-11-1) | Eugene Monroe, OT, Virginia | |
| 7 | Oakland Raiders (5-11) | Jeremy Maclin, WR, Missouri. | |
| 8 | Jacksonville Jaguars (5-11) | B.J. Raji, DT, Boston College | |
| 9 | Green Bay Packers (6-10) | Everette Brown, DE/OLB, Florida St. | |
| 10 | San Francisco 49ers (7-9) | Mark Sanchez, QB, USC | |
| 11 | Buffalo Bills (7-9) | Aaron Maybin, DE, Penn State | |
| 12 | Denver Broncos (8-8) | Tyson Jackson, DE, LSU | |
| 13 | Washington Redskins (8-8) | Michael Oher, OT, Ole Miss | |
| 14 | New Orleans Saints (8-8) | Malcolm Jenkins, CB/FS, Ohio State | |
| 15 | Houston Texans (8-8) | Clay Matthews, OLB, USC | |
| 16 | San Diego Chargers (8-8) | Andre Smith, OT, Alabama. | |
| 17 | New York Jets (9-7) | Chris Wells, RB, Ohio State | |
| 18 | Denver Broncos (Via Chicago) | Brian Cushing, OLB, USC | |
| 19 | Tampa Bay Buccaneers (9-7) | Peria Jerry, DT, Ole Miss | |
| 20 | Detroit Lions (9-7, Pick via Cowboys) | William Beatty, OT, UConn | |
| 21 | Philadelphia Eagles (9-6-1) | Brandon Pettigrew, TE, Ohio State | |
| 22 | Minnesota Vikings (10-6) | Vontae Davis, CB, Illinois | |
| 23 | New England Patriots (11-6) | Rey Maualuga, ILB, USC | |
| 24 | Atlanta Falcons (11-5) | James Lauranitis, ILB, Ohio State | |
| 25 | Miami Dolphins (11-5) | Darius Butler, CB, UConn | |
| 26 | Baltimore Ravens (11-5) | Darius Heyward-Bey, WR, Maryland: I really think it is realistic that he could fall here. | |
| 27 | Indianapolis Colts 12-4) | Evander “Ziggy” Hood, DT, Missouri | |
| 28 | Philadelphia Eagles (12-4; Pick via CAR) | Louis Delmas, S, Western Michigan | |
| 29 | New York Giants (12-4) | Kenny Britt, WR, Rutgers | |
| 30 | Tennessee Titans (13-3) | Percy Harvin, WR, Florida | |
| 31 | Arizona Cardinals (9-7) | Knowshown Moreno, RB, Georgia | |
| 32 | Pittsburgh Stinkers (12-4) | Alex Mack, C, California |